Before deleting a profile, stop all of the JVMs that are part of the profile.
Use the following command to delete a profile.
~]# /opt/IBM/WebSphere/your_server_name/bin/manageprofiles.sh -delete -profileName profile_name
C:\IBM\WebSphere\your_server_name\bin\manageprofiles.bat -delete -profileName profile_name
After the profile has been deleted, you may want to delete the remaining profile files.
~]# rm -rf /opt/IBM/WebSphere/your_server_name/profiles/your_profile_name